Directions

Close to Everything

FROM I-40 WEST (Coming from the East - RDU Airport, Raleigh, Wilmington)

  • Follow I-40 West to exit 279B, which is Route 147 North (Durham Freeway).
  • Continue on 147 North for approx. 11 miles to exit 16B, which is 15/501 South Bypass.
  • Follow 15/501 South for approx. 1 mile to exit 107, Duke University West Campus.
  • At the bottom of the exit turn left onto Cameron Blvd.
  • Continue on Cameron Blvd. to the 3rd traffic light, which is Science Drive.
  • Turn left at Science Drive.
  • Continue on Science Drive for ¼ mile and turn left onto Thomas Center Drive to reach the Entry Plaza of the JB Duke Hotel.

FROM I-40 EAST (Coming from the West - Chapel Hill, Winston-Salem, Asheville)

  • Follow I-40 East to exit 270, which is 15/501.
  • Turn left onto 15/501 North (towards Durham).
  • Continue on 15/501 North for approx. 2 miles and 15/501 Business will split to the left.
  • Stay to the right to remain on 15/501 North towards downtown Durham.
  • Follow 15/501 North for approx. 2 more miles to exit 107, Duke University West Campus.
  • At the bottom of the exit turn right onto Cameron Blvd.
  • Continue on Cameron Blvd to the second traffic light, which is Science Drive.
  • Turn left at Science Drive.
  • Continue on Science Drive for ¼ mile and turn left onto Thomas Center Drive to reach the Entry Plaza of the JB Duke Hotel.

FROM I-85 NORTH (Coming from the South - Greensboro, High Point, Charlotte)

  • Follow I-85 North to exit 172, which is Route 147 South (Durham Freeway).
  • Continue on 147 South for less than 1 mile to exit 16B, which is 15/501 South Bypass.
  • Follow 15/501 South approx. 1 mile to exit 107, Duke University West Campus.
  • At the bottom of the exit turn left onto Cameron Blvd.
  • Continue on Cameron Blvd to the 3rd traffic light, which is Science Drive.
  • Turn left at Science Drive.
  • Continue on Science Drive for ¼ mile and turn left onto Thomas Center Drive to reach the Entry Plaza of the JB Duke Hotel.

FROM I-85 SOUTH (Coming from the North - Virginia and Points North)

  • Follow I-85 South to 15/501 South Bypass (Exit 174A).
  • Follow 15/501 South approx. 1½ miles to exit 107, Duke University West Campus.
  • At the bottom of the exit turn left onto Cameron Blvd.
  • Continue on Cameron Blvd to the 3rd traffic light, which is Science Drive.
  • Turn left at Science Drive.
  • Continue on Science Drive for ¼ mile and turn left onto Thomas Center Drive to reach the Entry Plaza of the JB Duke Hotel.